ABC Transporters and CYP3A4 Mediate Drug Interactions between Enrofloxacin and Salinomycin Leading to Increased Risk of Drug Residues and Resistance.

Chen, Min; Yang, Yujuan; Ying, Yupeng; Huang, Jiamin; Sun, Mengyuan; Hong, Mian; Wang, Haizhen; Xie, Shuyu; Chen, Dongmei

Chen, Min; Yang, Yujuan; Ying, Yupeng; Huang, Jiamin; Sun, Mengyuan; Hong, Mian; Wang, Haizhen; Xie, Shuyu; Chen, Dongmei.

Affiliation

Chen M; National Reference Laboratory of Veterinary Drug Residues (HZAU), Wuhan 430070, China.
Yang Y; National Reference Laboratory of Veterinary Drug Residues (HZAU), Wuhan 430070, China.
Ying Y; National Reference Laboratory of Veterinary Drug Residues (HZAU), Wuhan 430070, China.
Huang J; National Reference Laboratory of Veterinary Drug Residues (HZAU), Wuhan 430070, China.
Sun M; National Reference Laboratory of Veterinary Drug Residues (HZAU), Wuhan 430070, China.
Hong M; National Reference Laboratory of Veterinary Drug Residues (HZAU), Wuhan 430070, China.
Wang H; National Reference Laboratory of Veterinary Drug Residues (HZAU), Wuhan 430070, China.
Xie S; National Reference Laboratory of Veterinary Drug Residues (HZAU), Wuhan 430070, China.
Chen D; MOA Laboratory for Risk Assessment of Quality and Safety of Livestock and Poultry Products, Huazhong Agricultural University, Wuhan 430070, China.

Antibiotics (Basel) ; 12(2)2023 Feb 17.

Article in En | MEDLINE | ID: mdl-36830313

Key words

ABC transporter; CYP3A4; drugdrug interactions; enrofloxacin; salinomycin; steric-like effect

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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: Antibiotics (Basel) Year: 2023 Document type: Article Affiliation country: China Country of publication: Switzerland

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