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A human antibody potently neutralizes RSV by targeting the conserved hydrophobic region of prefusion F.
Yi, Chunyan; Su, Caixia; Sun, Xiaoyu; Lu, Xiao; Si, Chuanya; Liu, Caixuan; Yang, Zhuo; Yuan, Hong; Huang, Yuying; Wen, Jing; He, Yonghui; Zhang, Yaguang; Ma, Liyan; Cong, Yao; Zhao, Gan; Ling, Zhiyang; Wang, Bin; Sun, Bing.
Affiliation
  • Yi C; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • Su C; Key Laboratory of Medical Molecular Virology (MOE/MOH), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Sun X; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • Lu X; Shanghai Institute of Infectious Disease and Biosecurity, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
  • Si C; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • Liu C; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • Yang Z; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • Yuan H; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • Huang Y; MedimScience.Co, Hangzhou, 311217, China.
  • Wen J; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • He Y; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • Zhang Y; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • Ma L; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • Cong Y; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • Zhao G; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China.
  • Ling Z; Key Laboratory of Medical Molecular Virology (MOE/MOH), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China. gzhao005@126.com.
  • Wang B; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences; University of Chinese Academy of Sciences, Shanghai, 200031, China. Zhiyangling@sibs.ac.cn.
  • Sun B; Key Laboratory of Medical Molecular Virology (MOE/MOH), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China. bwang139@163.com.
Sci China Life Sci ; 66(4): 729-742, 2023 04.
Article in En | MEDLINE | ID: mdl-36853487
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Syncytial Virus, Human / Respiratory Syncytial Virus Infections / Respiratory Syncytial Virus Vaccines Type of study: Prognostic_studies Limits: Child / Humans Language: En Journal: Sci China Life Sci Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: China Country of publication: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Syncytial Virus, Human / Respiratory Syncytial Virus Infections / Respiratory Syncytial Virus Vaccines Type of study: Prognostic_studies Limits: Child / Humans Language: En Journal: Sci China Life Sci Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: China Country of publication: China