[Psoriatic arthritis : Clinical challenges and pharmaceutical management]. / Psoriasisarthritis : Klinische Herausforderungen und medikamentöses Management.
Z Rheumatol
; 82(3): 220-232, 2023 Apr.
Article
in De
| MEDLINE
| ID: mdl-36856805
ABSTRACT
Psoriatic arthritis (PsA) is a systemic immune-mediated inflammatory disease of the musculoskeletal system, which is accompanied by a chronic and progressive course. It is characterized by different clinical manifestations and can severely impair the quality of life and function of patients due to the existing heterogeneity of the manifestations. The (early) diagnosis of PsA and individualized therapeutic management in routine clinical practice are difficult due to the enormous clinical variability. In addition to the appearance of arthritis of the peripheral joints, there can be involvement of the axial skeleton, skin psoriasis, nail psoriasis, enthesitis and dactylitis. The clinical appearance, course of the disease, risk factors and pathophysiological mechanisms of PsA have been extensively researched in recent decades. With the associated better understanding of the disease, new treatment options and goals for effective treatment have also been established.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Psoriasis
/
Arthritis, Psoriatic
Type of study:
Diagnostic_studies
/
Risk_factors_studies
/
Screening_studies
Aspects:
Patient_preference
Limits:
Humans
Language:
De
Journal:
Z Rheumatol
Year:
2023
Document type:
Article