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Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation.
de Carvalho Ribeiro, Marcelle; Iracheta-Vellve, Arvin; Babuta, Mrigya; Calenda, Charles D; Copeland, Christopher; Zhuang, Yuan; Lowe, Patrick P; Hawryluk, Danielle; Catalano, Donna; Cho, Yeonhee; Barton, Bruce; Dasarathy, Srinivasan; McClain, Craig; McCullough, Arthur J; Mitchell, Mack C; Nagy, Laura E; Radaeva, Svetlana; Lien, Egil; Golenbock, Douglas T; Szabo, Gyongyi.
Affiliation
  • de Carvalho Ribeiro M; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Iracheta-Vellve A; Monte Rosa Therapeutics, Boston, Massachusetts, 02210, USA.
  • Babuta M; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
  • Calenda CD; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Copeland C; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Zhuang Y; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Lowe PP; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Hawryluk D; Brigham and Women's General Hospital, Boston, Massachusetts, USA.
  • Catalano D; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Cho Y; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
  • Barton B; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
  • Dasarathy S; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
  • McClain C; Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
  • McCullough AJ; Center for Microbiome and Human Health, Lerner Research Institute of the Cleveland Clinic, Cleveland, Ohio, USA.
  • Mitchell MC; Department of Inflammation and Immunity, Lerner Research Institute of the Cleveland Clinic, Cleveland, Ohio, USA.
  • Nagy LE; Division of Gastroenterology, University of Louisville, Louisville, Kentucky, USA.
  • Radaeva S; Department of Gastroenterology, Hepatology and Nutrition, Cleveland Clinic, Cleveland, Ohio, USA.
  • Lien E; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
  • Golenbock DT; Center for Microbiome and Human Health, Lerner Research Institute of the Cleveland Clinic, Cleveland, Ohio, USA.
  • Szabo G; Department of Inflammation and Immunity, Lerner Research Institute of the Cleveland Clinic, Cleveland, Ohio, USA.
Hepatology ; 78(1): 225-242, 2023 07 01.
Article in En | MEDLINE | ID: mdl-36862512
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis / Hepatitis, Alcoholic Type of study: Etiology_studies / Risk_factors_studies Limits: Animals Language: En Journal: Hepatology Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hepatitis / Hepatitis, Alcoholic Type of study: Etiology_studies / Risk_factors_studies Limits: Animals Language: En Journal: Hepatology Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States