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Simple monocyclic pyrimidine analogs as microtubule targeting agents binding to the colchicine site.
Choudhary, Shruti; Kaku, Krishna; Robles, Andrew J; Hamel, Ernest; Mooberry, Susan L; Gangjee, Aleem.
Affiliation
  • Choudhary S; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh PA 15282, United States.
  • Kaku K; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh PA 15282, United States.
  • Robles AJ; Department of Pharmacology and the Mays Cancer Center, University of Texas Health Science Center, San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, United States.
  • Hamel E; Molecular Pharmacology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, Frederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, United States.
  • Mooberry SL; Department of Pharmacology and the Mays Cancer Center, University of Texas Health Science Center, San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, United States. Electronic address: mooberry@uthscsa.edu.
  • Gangjee A; Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh PA 15282, United States. Electronic address: gangjee@duq.edu.
Bioorg Med Chem ; 82: 117217, 2023 03 15.
Article in En | MEDLINE | ID: mdl-36889150
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colchicine / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2023 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colchicine / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2023 Document type: Article Affiliation country: United States Country of publication: United kingdom