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Quantification of levetiracetam in plasma and urine and its application to a pharmacokinetic study of traumatic brain injury patients.
Adiraju, Santosh Ks; Sumi, Chandra D; Pandey, Saurabh; Cotta, Menino O; Roberts, Jason A; Lipman, Jeffrey; Wallis, Steven C; Parker, Suzanne L.
Affiliation
  • Adiraju SK; The University of Queensland Centre for Clinical Research, The University of Queensland, Herston, QLD, 4029, Australia.
  • Sumi CD; The University of Queensland Centre for Clinical Research, The University of Queensland, Herston, QLD, 4029, Australia.
  • Pandey S; The University of Queensland Centre for Clinical Research, The University of Queensland, Herston, QLD, 4029, Australia.
  • Cotta MO; The University of Queensland Centre for Clinical Research, The University of Queensland, Herston, QLD, 4029, Australia.
  • Roberts JA; The University of Queensland Centre for Clinical Research, The University of Queensland, Herston, QLD, 4029, Australia.
  • Lipman J; Department of Intensive Care Medicine, Royal Brisbane & Women's Hospital, Herston, QLD, 4029, Australia.
  • Wallis SC; Division of Anaesthesiology Critical Care Emergency & Pain Medicine, Nîmes University Hospital, University of Montpellier, Nîmes, 30900, France.
  • Parker SL; Department of Pharmacy, Royal Brisbane & Women's Hospital, Herston, QLD, 4029, Australia.
Bioanalysis ; 15(1): 31-42, 2023 Jan.
Article in En | MEDLINE | ID: mdl-36927087
Levetiracetam is a drug that is used for the prevention or treatment of seizure. This study aimed to design a method that would be suitable for measuring levetiracetam in human plasma and urine. The method was subsequently applied to a clinical study of patients with severe traumatic brain injury.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tandem Mass Spectrometry / Brain Injuries, Traumatic Limits: Humans Language: En Journal: Bioanalysis Year: 2023 Document type: Article Affiliation country: Australia Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tandem Mass Spectrometry / Brain Injuries, Traumatic Limits: Humans Language: En Journal: Bioanalysis Year: 2023 Document type: Article Affiliation country: Australia Country of publication: United kingdom