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Functional characterization and in vitro pharmacological rescue of KCNQ2 pore mutations associated with epileptic encephalopathy.
Yang, Gui-Mei; Tian, Fu-Yun; Shen, Yan-Wen; Yang, Chuan-Yan; Yuan, Hui; Li, Ping; Gao, Zhao-Bing.
Affiliation
  • Yang GM; School of Pharmacy, Zunyi Medical University, Zunyi, 563000, China.
  • Tian FY; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.
  • Shen YW; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China. tianfuyun@zidd.ac.cn.
  • Yang CY; Center for Neurological and Psychiatric Research and Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China. tianfuyun@zidd.ac.cn.
  • Yuan H; Department of Pediatrics, The First Medical Center of PLA General Hospital, Beijing, 100853, China.
  • Li P; Department of Pediatric neurology, Children's Hospital of Fudan university at Xiamen, Xiamen, 361006, China.
  • Gao ZB; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, 528400, China.
Acta Pharmacol Sin ; 44(8): 1589-1599, 2023 Aug.
Article in En | MEDLINE | ID: mdl-36932231
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Diseases / KCNQ2 Potassium Channel Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2023 Document type: Article Affiliation country: China Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Diseases / KCNQ2 Potassium Channel Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2023 Document type: Article Affiliation country: China Country of publication: United States