Secoiridoids from the traditional Chinese medicine Swertia pseudochinensis.
Phytochemistry
; 210: 113642, 2023 Jun.
Article
in En
| MEDLINE
| ID: mdl-36933879
ABSTRACT
Detailed phytochemical investigation on the traditional Chinese medicine Swertia pseudochinensis Hara led to the isolation of ten undescribed secoiridoids and fifteen known analogs. Their structures were elucidated by extensive spectroscopic analysis (including 1D and 2D NMR, and HRESIMS). Selected isolates were assayed for their anti-inflammatory and antibacterial activities, and moderate anti-inflammatory activity via inhibiting the secretion of cytokines IL-6 and TNF-α in macrophages RAW264.7 induced by LPS were observed. Antibacterial activity against Staphylococcus aureus was not found at 100 µM.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Drugs, Chinese Herbal
/
Swertia
Type of study:
Diagnostic_studies
Language:
En
Journal:
Phytochemistry
Year:
2023
Document type:
Article