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The Influence of Multilevel Spinal Deformity Surgery on the EuroQol 5 Dimensions' (EQ-5D) Questionnaire and Residential Status in the Elderly: A Prospective, Observational, Multicenter Study.
Jentzsch, Thorsten; Lewis, Stephen J; Oitment, Colby; Rienmüller, Anna; Martin, Allan R; Nielsen, Christopher J; Shear-Yashuv, Hananel; de Kleuver, Marinus; Qiu, Yong; Matsuyama, Yukihiro; Lenke, Lawrence G; Alanay, Ahmet; Pellisé-Urquiza, Ferran; Cheung, Kenneth M C; Spruit, Maarten; Polly, David W; Sembrano, Jonathan N; Shaffrey, Christopher I; Smith, Justin S; Kelly, Michael P; Dahl, Benny; Berven, Sigurd H.
Affiliation
  • Jentzsch T; Division of Orthopaedic Surgery, Arthritis Program, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
  • Lewis SJ; Department of Surgery, University of Toronto, Toronto, ON, Canada.
  • Oitment C; Department of Orthopaedics, University of Zurich, Balgrist University Hospital, Zurich, Switzerland.
  • Rienmüller A; Division of Orthopaedic Surgery, Arthritis Program, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
  • Martin AR; Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada, Canada.
  • Nielsen CJ; Department of Orthopedic and Trauma Surgery, Medical University Vienna, Vienna, Austria.
  • Shear-Yashuv H; Department of Neurological Surgery, University of California - Davis, Sacramento, CA, USA.
  • de Kleuver M; Division of Orthopaedic Surgery, Arthritis Program, Toronto Western Hospital, University Health Network, Toronto, ON, Canada.
  • Qiu Y; Department of Orthopaedic, Hebrew University, Hadassah Medical Center, Jerusalem, Israel.
  • Matsuyama Y; Department of Orthopedics, Medical Center, Radboud University, Nijmegen, Gelderland, The Netherlands.
  • Lenke LG; Spine Surgery, Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.
  • Alanay A; Department of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
  • Pellisé-Urquiza F; Department of Orthopedic Surgery, The Spine Hospital, Medical Center, Columbia University, New York, NY, USA.
  • Cheung KMC; Department of Orthopedics and Traumatology, Acibadem Mehmet ali Aydinlar University, Istanbul, Turkey.
  • Spruit M; Hospital Universitari de la Vall d'Hebron, Barcelona, Spain.
  • Polly DW; Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong.
  • Sembrano JN; Sint Maartenskliniek Nijmegen, Gelderland, the Netherlands.
  • Shaffrey CI; Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, USA.
  • Smith JS; Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, USA.
  • Kelly MP; Department of Orthopaedic Surgery, Duke University, Durham, NC, USA.
  • Dahl B; Department of Neurosurgery, University of Virginia, Charlottesville, VA, USA.
  • Berven SH; Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, USA.
Global Spine J ; : 21925682231162574, 2023 Mar 21.
Article in En | MEDLINE | ID: mdl-36943086
ABSTRACT
STUDY

DESIGN:

Multicenter, international prospective study.

OBJECTIVE:

This study investigated the clinical outcome up to 2 years after multi-level spinal deformity surgery in the elderly by reporting the minimal clinically important difference (MCID) of EuroQol 5-dimensions (EQ-5D), EQ-VAS, and residential status.

METHODS:

As an ancillary study of 219 patients ≥60 years with spinal deformity undergoing primary instrumented fusion surgery of ≥5 levels, this study focuses on EQ-5D (3-L) as the primary outcome and EQ-VAS and residential status as secondary outcomes. Data on EQ-5D were compared between pre-operatively and postoperatively at 10 weeks, 12 months, and 24 months. An anchor-based approach was used to calculate the MCID.

RESULTS:

The EQ-5D index and EQ-VAS, respectively, improved significantly at each time point compared to pre-operatively (from .53 (SD .21) and 55.6 (SD 23.0) pre-operatively to .64 (SD .18) and 65.8 (SD 18.7) at 10 weeks, .74 (SD .18) and 72.7 (SD 18.1) at 12 months, and .73 (SD .20) and 70.4 (SD 20.4) at 24 months). 217 (99.1%) patients lived at home pre-operatively, while 186 (88.6%), 184 (98.4%), and 172 (100%) did so at 10 weeks, 12 months, and 24 months, respectively. Our calculated MCID for the EQ-5D index at 1 year was .22 (95% CI .15-.29).

CONCLUSIONS:

The EQ-5D index significantly increased at each time point over 24 months after ≥5 level spinal deformity surgery in elderly patients. The MCID of the EQ-5D-3 L was .22. Patients living at home pre-operatively can expect to be able to live at home 2 years postoperatively.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials / Observational_studies Language: En Journal: Global Spine J Year: 2023 Document type: Article Affiliation country: Canada
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials / Observational_studies Language: En Journal: Global Spine J Year: 2023 Document type: Article Affiliation country: Canada