Exon-18-EGFR Mutated Transformed Small-Cell Lung Cancer: A Case Report and Literature Review.
Curr Oncol
; 30(3): 3494-3499, 2023 03 20.
Article
in En
| MEDLINE
| ID: mdl-36975478
ABSTRACT
Small-cell lung cancer (SCLC) transformation from EGFR mutant adenocarcinoma is a rare entity that is considered to be a new phenotype of SCLC. While transformation from adenocarcinoma (ADC) with EGFR exon 19 deletions and exon 21 L858R point mutations has been described, to our knowledge, no cases of transformation to SCLC from exon-18-mutated ADC have been reported. We reported a clinical case of a patient with exon-18-EGFR-transformed SCLC, and we performed a systematic review of the literature.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Adenocarcinoma
/
Small Cell Lung Carcinoma
/
Lung Neoplasms
Type of study:
Systematic_reviews
Limits:
Humans
Language:
En
Journal:
Curr Oncol
Year:
2023
Document type:
Article
Affiliation country:
Italy