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Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes.
Toikumo, Sylvanus; Jennings, Mariela V; Pham, Benjamin K; Lee, Hyunjoon; Mallard, Travis T; Bianchi, Sevim B; Meredith, John J; Vilar-Ribó, Laura; Xu, Heng; Hatoum, Alexander S; Johnson, Emma C; Pazdernik, Vanessa; Jinwala, Zeal; Pakala, Shreya R; Leger, Brittany S; Niarchou, Maria; Ehinmowo, Michael; Jenkins, Greg D; Batzler, Anthony; Pendegraft, Richard; Palmer, Abraham A; Zhou, Hang; Biernacka, Joanna M; Coombes, Brandon J; Gelernter, Joel; Xu, Ke; Hancock, Dana B; Cox, Nancy J; Smoller, Jordan W; Davis, Lea K; Justice, Amy C; Kranzler, Henry R; Kember, Rachel L; Sanchez-Roige, Sandra.
Affiliation
  • Toikumo S; Mental Illness Research, Education and Clinical Center, Crescenz VAMC, Philadelphia, PA, USA.
  • Jennings MV; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Pham BK; Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
  • Lee H; Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
  • Mallard TT; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Bianchi SB; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Meredith JJ; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.
  • Vilar-Ribó L; Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
  • Xu H; Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
  • Hatoum AS; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Johnson EC; Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
  • Pazdernik V; Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri, USA.
  • Jinwala Z; Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri, USA.
  • Pakala SR; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
  • Leger BS; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Niarchou M; Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
  • Ehinmowo M; Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
  • Jenkins GD; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Batzler A; Department of Psychology, University of Ibadan, Nigeria.
  • Palmer AA; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
  • Zhou H; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
  • Biernacka JM; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
  • Coombes BJ; Department of Psychiatry, University of California San Diego, San Diego, CA, USA.
  • Gelernter J; Institute for Genomic Medicine, University of California San Diego, La Jolla, CA, USA.
  • Xu K; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
  • Hancock DB; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.
  • Cox NJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
  • Smoller JW; Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA.
  • Davis LK; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
  • Justice AC; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
  • Kranzler HR; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.
  • Kember RL; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
  • Sanchez-Roige S; Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.
medRxiv ; 2023 Sep 18.
Article in En | MEDLINE | ID: mdl-37034728
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Language: En Journal: MedRxiv Year: 2023 Document type: Article Affiliation country: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Language: En Journal: MedRxiv Year: 2023 Document type: Article Affiliation country: United States