Photobiomodulation for knee osteoarthritis: a model-based dosimetry study.
Biomed Opt Express
; 14(4): 1800-1817, 2023 Apr 01.
Article
in En
| MEDLINE
| ID: mdl-37078045
ABSTRACT
LED-based photobiomodulation (LED-PBM) for the treatment of knee osteoarthritis (KOA) is a promising technology. However, the light dose at the targeted tissue, which dominates the phototherapy effectiveness, is difficult to measure. This paper studied the dosimetric issues in the phototherapy of KOA by developing an optical model of the knee and performing Monte Carlo (MC) simulation. The model was validated by the tissue phantom and knee experiments. In the study, we investigated the effect of luminous characteristics of the light source, such as divergence angle, wavelength and irradiation position, on the treatment doses for PBM. The result showed that the divergence angle and the wavelength of the light source have a significant impact on the treatment doses. The optimal irradiation location was on both sides of the patella, where the largest dose could reach the articular cartilage. This optical model can be used to determine the key parameters in phototherapy and help the phototherapy of KOA patients.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Prognostic_studies
Language:
En
Journal:
Biomed Opt Express
Year:
2023
Document type:
Article
Affiliation country:
China