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Fibroblast activation protein targeted radiotherapy induces an immunogenic tumor microenvironment and enhances the efficacy of PD-1 immune checkpoint inhibition.
Zboralski, Dirk; Osterkamp, Frank; Christensen, Esben; Bredenbeck, Anne; Schumann, Anne; Hoehne, Aileen; Schneider, Eberhard; Paschke, Matthias; Ungewiss, Jan; Haase, Christian; Robillard, Liliane; Simmons, Andrew D; Harding, Thomas C; Nguyen, Minh.
Affiliation
  • Zboralski D; 3B Pharmaceuticals GmbH, Magnusstraße 11, D-12489, Berlin, Germany. dirk.zboralski@3b-pharma.com.
  • Osterkamp F; 3B Pharmaceuticals GmbH, Magnusstraße 11, D-12489, Berlin, Germany.
  • Christensen E; Minerva Imaging ApS, Ølstykke, Denmark.
  • Bredenbeck A; 3B Pharmaceuticals GmbH, Magnusstraße 11, D-12489, Berlin, Germany.
  • Schumann A; 3B Pharmaceuticals GmbH, Magnusstraße 11, D-12489, Berlin, Germany.
  • Hoehne A; 3B Pharmaceuticals GmbH, Magnusstraße 11, D-12489, Berlin, Germany.
  • Schneider E; 3B Pharmaceuticals GmbH, Magnusstraße 11, D-12489, Berlin, Germany.
  • Paschke M; 3B Pharmaceuticals GmbH, Magnusstraße 11, D-12489, Berlin, Germany.
  • Ungewiss J; 3B Pharmaceuticals GmbH, Magnusstraße 11, D-12489, Berlin, Germany.
  • Haase C; 3B Pharmaceuticals GmbH, Magnusstraße 11, D-12489, Berlin, Germany.
  • Robillard L; Clovis Oncology, Inc., CO, Boulder, USA.
  • Simmons AD; Clovis Oncology, Inc., CO, Boulder, USA.
  • Harding TC; Clovis Oncology, Inc., CO, Boulder, USA.
  • Nguyen M; Clovis Oncology, Inc., CO, Boulder, USA.
Eur J Nucl Med Mol Imaging ; 50(9): 2621-2635, 2023 07.
Article in En | MEDLINE | ID: mdl-37086273
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD8-Positive T-Lymphocytes / Immune Checkpoint Inhibitors Type of study: Prognostic_studies Limits: Animals Language: En Journal: Eur J Nucl Med Mol Imaging Journal subject: MEDICINA NUCLEAR Year: 2023 Document type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD8-Positive T-Lymphocytes / Immune Checkpoint Inhibitors Type of study: Prognostic_studies Limits: Animals Language: En Journal: Eur J Nucl Med Mol Imaging Journal subject: MEDICINA NUCLEAR Year: 2023 Document type: Article Affiliation country: Germany