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Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors.
Xiao, Zebin; Todd, Leslie; Huang, Li; Noguera-Ortega, Estela; Lu, Zhen; Huang, Lili; Kopp, Meghan; Li, Yue; Pattada, Nimisha; Zhong, Wenqun; Guo, Wei; Scholler, John; Liousia, Maria; Assenmacher, Charles-Antoine; June, Carl H; Albelda, Steven M; Puré, Ellen.
Affiliation
  • Xiao Z; Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Todd L; Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Huang L; Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Noguera-Ortega E; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Lu Z; Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Huang L; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Kopp M; Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Li Y; Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Pattada N; Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Zhong W; Department of Biology, School of Arts & Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Guo W; Department of Biology, School of Arts & Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Scholler J; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Liousia M; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Assenmacher CA; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • June CH; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Albelda SM; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Puré E; Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
bioRxiv ; 2023 Aug 07.
Article in En | MEDLINE | ID: mdl-37090547
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2023 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2023 Document type: Article Affiliation country: United States