Transvenous occlusion of incompetent pelvic veins to treat chronic pelvic pain in women: A randomised controlled trial.
BJOG
; 130(11): 1362-1369, 2023 10.
Article
in En
| MEDLINE
| ID: mdl-37095614
ABSTRACT
OBJECTIVE:
To investigate the effectiveness of transvenous occlusion of incompetent pelvic veins in women presenting with chronic pelvic pain (CPP) in improving symptoms and quality of life.DESIGN:
Patient-blinded randomised controlled trial with objective outcome measures. Results were analysed on an intention-to-treat basis.SETTING:
Gynaecology and Vascular Surgery Services of two teaching hospitals in northwest England. POPULATION Sixty women aged 18-54 years presenting with CPP after exclusion of other pathology, and who were found to have pelvic vein incompetence.METHODS:
Participants were randomised and assigned to contrast venography alone or contrast venography plus transvenous occlusion of the incompetent pelvic veins. MAIN OUTCOMEMEASURE:
The primary outcome was change in pain score measured using the short-form McGill Pain Score (SF-MPQ) and the Visual Analogue Score (VAS) recorded at 12 months post-randomisation. Secondary outcomes included quality of life using the EQ-5D instrument, symptomatic improvement and procedure-related complications.RESULTS:
Sixty participants were randomised to transvenous occlusion of incompetent pelvic veins or venography only. At 12 months, median pain scored 2 (3-10) in the intervention group versus 9 (5-22) in controls (p = 0.016). Pain on the VAS scored 15 (0-3) versus 53 (20-71), respectively (p = 0.002). Median EQ-5D improved after intervention from 0.79 (0.74-0.84) to 0.84 (0.79-1.00; p = 0.008) over 12 months. No major complications were reported.CONCLUSION:
Transvenous occlusion of pelvic vein incompetence reduced pain scores, improved quality of life and diminished symptom burden with no major reported complications. TRIAL REGISTRATION ISRCTN 15091500.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pelvis
/
Quality of Life
Type of study:
Clinical_trials
/
Etiology_studies
Aspects:
Patient_preference
Limits:
Female
/
Humans
Country/Region as subject:
Europa
Language:
En
Journal:
BJOG
Journal subject:
GINECOLOGIA
/
OBSTETRICIA
Year:
2023
Document type:
Article
Affiliation country:
United kingdom