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Small Molecule Inhibition of an Exopolysaccharide Modification Enzyme is a Viable Strategy To Block Pseudomonas aeruginosa Pel Biofilm Formation.
Razvi, Erum; DiFrancesco, Benjamin R; Wasney, Gregory A; Morrison, Zachary A; Tam, John; Auger, Anick; Baker, Perrin; Alnabelseya, Noor; Rich, Jacquelyn D; Sivarajah, Piyanka; Whitfield, Gregory B; Harrison, Joe J; Melnyk, Roman A; Nitz, Mark; Howell, P Lynne.
Affiliation
  • Razvi E; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • DiFrancesco BR; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
  • Wasney GA; Department of Chemistry, University of Toronto, Toronto, Ontario, Canada.
  • Morrison ZA; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Tam J; The Structural & Biophysical Core Facility, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Auger A; Department of Chemistry, University of Toronto, Toronto, Ontario, Canada.
  • Baker P; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Alnabelseya N; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Rich JD; SPARC BioCentre, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Sivarajah P; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Whitfield GB; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Harrison JJ; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
  • Melnyk RA; Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada.
  • Nitz M; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Howell PL; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
Microbiol Spectr ; 11(3): e0029623, 2023 06 15.
Article in En | MEDLINE | ID: mdl-37098898
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides, Bacterial / Pseudomonas aeruginosa Limits: Humans Language: En Journal: Microbiol Spectr Year: 2023 Document type: Article Affiliation country: Canada
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides, Bacterial / Pseudomonas aeruginosa Limits: Humans Language: En Journal: Microbiol Spectr Year: 2023 Document type: Article Affiliation country: Canada