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Lymphatic disorders caused by mosaic, activating KRAS variants respond to MEK inhibition.
Sheppard, Sarah E; March, Michael E; Seiler, Christoph; Matsuoka, Leticia S; Kim, Sophia E; Kao, Charlly; Rubin, Adam I; Battig, Mark R; Khalek, Nahla; Schindewolf, Erica; O'Connor, Nora; Pinto, Erin; Priestley, Jessica Rc; Sanders, Victoria R; Niazi, Rojeen; Ganguly, Arupa; Hou, Cuiping; Slater, Diana; Frieden, Ilona J; Huynh, Thy; Shieh, Joseph T; Krantz, Ian D; Guerrero, Jessenia C; Surrey, Lea F; Biko, David M; Laje, Pablo; Castelo-Soccio, Leslie; Nakano, Taizo A; Snyder, Kristen; Smith, Christopher L; Li, Dong; Dori, Yoav; Hakonarson, Hakon.
Affiliation
  • Sheppard SE; Center for Applied Genomics.
  • March ME; Division of Human Genetics, and.
  • Seiler C; Center for Applied Genomics.
  • Matsuoka LS; Zebrafish Core, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Kim SE; Center for Applied Genomics.
  • Kao C; Center for Applied Genomics.
  • Rubin AI; Center for Applied Genomics.
  • Battig MR; Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Khalek N; Center for Applied Genomics.
  • Schindewolf E; Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment and.
  • O'Connor N; Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment and.
  • Pinto E; Center for Applied Genomics.
  • Priestley JR; Jill and Mark Fishman Center for Lymphatic Disorders, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Sanders VR; Division of Human Genetics, and.
  • Niazi R; Division of Human Genetics, and.
  • Ganguly A; Genetic Diagnostic Laboratory, Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Hou C; Genetic Diagnostic Laboratory, Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Slater D; Center for Applied Genomics.
  • Frieden IJ; Center for Applied Genomics.
  • Huynh T; Department of Dermatology and.
  • Shieh JT; Department of Dermatology and.
  • Krantz ID; Division of Medical Genetics, Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA.
  • Guerrero JC; Division of Human Genetics, and.
  • Surrey LF; Roberts Individualized Medical Genetics Center, Division of Human Genetics.
  • Biko DM; Department of Pathology.
  • Laje P; Department of Pathology.
  • Castelo-Soccio L; Department of Radiology.
  • Nakano TA; Department of Surgery; and.
  • Snyder K; Dermatology Section, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Smith CL; Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora, Colorado, USA.
  • Li D; Division of Oncology, Cancer Center, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Dori Y; Jill and Mark Fishman Center for Lymphatic Disorders, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Hakonarson H; Center for Applied Genomics.
JCI Insight ; 8(9)2023 05 08.
Article in En | MEDLINE | ID: mdl-37154160
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Zebrafish / Proto-Oncogene Proteins p21(ras) Limits: Animals / Humans Language: En Journal: JCI Insight Year: 2023 Document type: Article Country of publication: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Zebrafish / Proto-Oncogene Proteins p21(ras) Limits: Animals / Humans Language: En Journal: JCI Insight Year: 2023 Document type: Article Country of publication: United States