Investigating multifaceted action of ibuprofen derivatives towards cox isozymes and interleukin-6 (IL-6) site correlating with various target sites.

Kaur, Mandeep; Gupta, Pramodkumar P; Jain, Anmol; Kaur, Gurmeet; Kaur, Amandeep; Bansal, Manisha

Kaur, Mandeep; Gupta, Pramodkumar P; Jain, Anmol; Kaur, Gurmeet; Kaur, Amandeep; Bansal, Manisha.

Affiliation

Kaur M; Department of Chemistry, Punjabi University, Patiala, India.
Gupta PP; School of Biotechnology and Bioinformatics, D Y Patil Deemed to be University, Navi Mumbai, Maharashtra, India.
Jain A; Department of Chemistry, Punjabi University, Patiala, India.
Kaur G; Department of Chemistry, Punjabi University, Patiala, India.
Kaur A; Department of Chemistry, Punjabi University, Patiala, India.
Bansal M; Department of Chemistry, Punjabi University, Patiala, India.

J Biomol Struct Dyn ; 42(5): 2410-2423, 2024 Mar.

Article in En | MEDLINE | ID: mdl-37154526

Subject(s)

Ibuprofen; Interleukin-6; Prostaglandin-Endoperoxide Synthases; Humans; Anti-Inflammatory Agents/pharmacology; Ibuprofen/pharmacology; Inflammation/drug therapy; Isoenzymes/drug effects; Molecular Docking Simulation; Prostaglandin-Endoperoxide Synthases/drug effects

Key words

Compound 3; Computational studies; Structural features toward various target sites; Synthesis; anti-inflammatory activity in vitro

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ibuprofen / Interleukin-6 / Prostaglandin-Endoperoxide Synthases Limits: Humans Language: En Journal: J Biomol Struct Dyn Year: 2024 Document type: Article Affiliation country: India Country of publication: United kingdom

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