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Discovery and Optimization of Novel Biphenyl Derivatives Bearing Cyclopropyl Linkage as Potent Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Inhibitors.
Jing, Tongfei; Zhang, Zhijing; Kang, Zhenghui; Mo, Jianshan; Yue, Xiaotong; Lin, Ziyou; Fu, Xiang; Liu, Chang; Ma, Hang; Zhang, Xiaolei; Hu, Wenhao.
Affiliation
  • Jing T; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
  • Zhang Z; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
  • Kang Z; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
  • Mo J; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
  • Yue X; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
  • Lin Z; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
  • Fu X; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
  • Liu C; Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island 02881, United States.
  • Ma H; Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island 02881, United States.
  • Zhang X; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
  • Hu W; Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, P. R. China.
J Med Chem ; 66(10): 6811-6835, 2023 05 25.
Article in En | MEDLINE | ID: mdl-37159395
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B7-H1 Antigen / Programmed Cell Death 1 Receptor Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B7-H1 Antigen / Programmed Cell Death 1 Receptor Limits: Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Country of publication: United States