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Systematic Review on Magnetic Resonance Angiography with Vessel Wall Imaging for the Characterization of Symptomatic Carotid Artery Plaque.
Lozano Gonzalez, Roberta; Singh, Rahul B; Virador, Gabriel M; Barrett, Kevin M; Farres, Houssam; Miller, David A; Meschia, James F; Sandhu, Sukhwinder J S; Erben, Young.
Affiliation
  • Lozano Gonzalez R; Division of Vascular and Endovascular Surgery, Mayo Clinic, Jacksonville, FL.
  • Singh RB; Department of Radiology, Mayo Clinic, Jacksonville, FL.
  • Virador GM; Department of Radiology, Mayo Clinic, Jacksonville, FL.
  • Barrett KM; Department of Neurology, Mayo Clinic, Jacksonville, FL.
  • Farres H; Division of Vascular and Endovascular Surgery, Mayo Clinic, Jacksonville, FL.
  • Miller DA; Department of Radiology, Mayo Clinic, Jacksonville, FL.
  • Meschia JF; Department of Neurology, Mayo Clinic, Jacksonville, FL.
  • Sandhu SJS; Department of Radiology, Mayo Clinic, Jacksonville, FL.
  • Erben Y; Division of Vascular and Endovascular Surgery, Mayo Clinic, Jacksonville, FL. Electronic address: erben.young@mayo.edu.
Ann Vasc Surg ; 95: 224-232, 2023 Sep.
Article in En | MEDLINE | ID: mdl-37164170
ABSTRACT

BACKGROUND:

To perform a systematic literature review to assess the usefulness of performing magnetic resonance angiography (MRA) with vessel wall imaging (VWI) sequences for the assessment of symptomatic carotid artery plaques and the identification of risky plaque features predisposing for stroke.

METHODS:

We performed a systematic review of the literature pertaining to MRA with VWI techniques in patients with carotid artery disease, focusing on symptomatic patients' plaque features and morphology. Independent reviewers screened and analyzed data extracted from eligible studies, and a modified Newcastle-Ottawa Scale was used to appraise the quality of the design and content of the selected manuscripts to achieve an accurate interpretation.

RESULTS:

This review included nineteen peer-reviewed manuscripts, all of them including MRA and VWI assessments of the symptomatic carotid artery plaque. We focused on patients' comorbidities and reviewed plaque features, including intraplaque hemorrhage, a lipid-rich necrotic core, a ruptured fibrous cap, and plaque ulceration.

CONCLUSIONS:

MRA with VWI is a useful tool in the evaluation of carotid artery plaques. This imaging technique allows clinicians to identify plaques at risk of causing a neurovascular event. The presence of intraplaque hemorrhage, plaque ulceration, a ruptured fibrous cap, and a lipid-rich necrotic core are associated with neurovascular symptoms. The timely identification of these features could have a positive impact on neurovascular event prevention.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carotid Stenosis / Plaque, Atherosclerotic Type of study: Diagnostic_studies / Systematic_reviews Limits: Humans Language: En Journal: Ann Vasc Surg Journal subject: ANGIOLOGIA Year: 2023 Document type: Article Country of publication: HOLANDA / HOLLAND / NETHERLANDS / NL / PAISES BAJOS / THE NETHERLANDS

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carotid Stenosis / Plaque, Atherosclerotic Type of study: Diagnostic_studies / Systematic_reviews Limits: Humans Language: En Journal: Ann Vasc Surg Journal subject: ANGIOLOGIA Year: 2023 Document type: Article Country of publication: HOLANDA / HOLLAND / NETHERLANDS / NL / PAISES BAJOS / THE NETHERLANDS