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Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response.
Pagadala, Meghana; Sears, Timothy J; Wu, Victoria H; Pérez-Guijarro, Eva; Kim, Hyo; Castro, Andrea; Talwar, James V; Gonzalez-Colin, Cristian; Cao, Steven; Schmiedel, Benjamin J; Goudarzi, Shervin; Kirani, Divya; Au, Jessica; Zhang, Tongwu; Landi, Teresa; Salem, Rany M; Morris, Gerald P; Harismendy, Olivier; Patel, Sandip Pravin; Alexandrov, Ludmil B; Mesirov, Jill P; Zanetti, Maurizio; Day, Chi-Ping; Fan, Chun Chieh; Thompson, Wesley K; Merlino, Glenn; Gutkind, J Silvio; Vijayanand, Pandurangan; Carter, Hannah.
Affiliation
  • Pagadala M; Biomedical Sciences Program, University of California San Diego, La Jolla, CA, 92093, USA.
  • Sears TJ; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.
  • Wu VH; Department of Pharmacology, UCSD Moores Cancer Center, La Jolla, CA, 92093, USA.
  • Pérez-Guijarro E; Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
  • Kim H; Undergraduate Bioengineering Program, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, 92093, USA.
  • Castro A; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.
  • Talwar JV; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.
  • Gonzalez-Colin C; La Jolla Institute for Immunology, La Jolla, CA, 92037, USA.
  • Cao S; Division of Epidemiology, Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, 92093, USA.
  • Schmiedel BJ; La Jolla Institute for Immunology, La Jolla, CA, 92037, USA.
  • Goudarzi S; Canyon Crest Academy, San Diego, CA, 92130, USA.
  • Kirani D; Undergraduate Biology and Bioinformatics Program, University of California San Diego, La Jolla, CA, 92093, USA.
  • Au J; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.
  • Zhang T; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
  • Landi T; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
  • Salem RM; Division of Epidemiology, Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, 92093, USA.
  • Morris GP; Department of Pathology, University of California San Diego, La Jolla, CA, 92093, USA.
  • Harismendy O; Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, CA, 92093, USA.
  • Patel SP; Division of Biomedical Informatics, Department of Medicine, University of California San Diego School of Medicine, La Jolla, CA, 92093, USA.
  • Alexandrov LB; Center for Personalized Cancer Therapy, Division of Hematology and Oncology, UC San Diego Moores Cancer Center, San Diego, CA, 92037, USA.
  • Mesirov JP; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, 92093, USA.
  • Zanetti M; Department of Bioengineering, University of California San Diego, La Jolla, CA, 92093, USA.
  • Day CP; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.
  • Fan CC; Department of Medicine, Division of Medical Genetics, University of California San Diego, La Jolla, CA, 92093, USA.
  • Thompson WK; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.
  • Merlino G; The Laboratory of Immunology and Department of Medicine, University of California San Diego, La Jolla, CA, 92093, USA.
  • Gutkind JS; Laboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
  • Vijayanand P; Center for Population Neuroscience and Genetics, Laureate Institute for Brain Research, Tulsa, OK, 74136, USA.
  • Carter H; Department of Radiology, University of California San Diego, La Jolla, CA, 92093, USA.
Nat Commun ; 14(1): 2744, 2023 05 12.
Article in En | MEDLINE | ID: mdl-37173324
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunotherapy / Neoplasms Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunotherapy / Neoplasms Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: United States Country of publication: United kingdom