Diversity of Cationic Antimicrobial Peptides in Black Cumin (Nigella sativa L.) Seeds.
Int J Mol Sci
; 24(9)2023 Apr 29.
Article
in En
| MEDLINE
| ID: mdl-37175769
ABSTRACT
Black cumin (Nigella sativa L.) is known to possess a wide variety of antimicrobial peptides belonging to different structural families. Three novel antimicrobial peptides have been isolated from black cumin seeds. Two of them were attributed as members of the non-specific lipid transfer proteins family, and one as a defensin. We have made an attempt of using the proteomic approach for novel antimicrobial peptides search in N. sativa seeds as well. The use of a well-established approach that includes extraction and fractionation stages remains relevant even in the case of novel peptides search because of the lacking N. sativa genome data. Novel peptides demonstrate a spectrum of antimicrobial activity against plant pathogenic organisms that may cause economically important crop diseases. These results obtained allow considering these molecules as candidates to be applied in "next-generation" biopesticides development for agricultural use.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Nigella sativa
Limits:
Humans
Language:
En
Journal:
Int J Mol Sci
Year:
2023
Document type:
Article
Affiliation country:
RUSSIA