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Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss.
Zhu, Xianbing; Fu, Zheng; Chen, Shary Y; Ong, Dionzie; Aceto, Giulio; Ho, Rebecca; Steinberger, Jutta; Monast, Anie; Pilon, Virginie; Li, Eunice; Ta, Monica; Ching, Kyle; Adams, Bianca N; Negri, Gian L; Choiniere, Luc; Fu, Lili; Pavlakis, Kitty; Pirrotte, Patrick; Avizonis, Daina Z; Trent, Jeffrey; Weissman, Bernard E; Klein Geltink, Ramon I; Morin, Gregg B; Park, Morag; Huntsman, David G; Foulkes, William D; Wang, Yemin; Huang, Sidong.
Affiliation
  • Zhu X; Department of Biochemistry, McGill University, Montreal, QC, Canada.
  • Fu Z; Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, Canada.
  • Chen SY; Department of Biochemistry, McGill University, Montreal, QC, Canada.
  • Ong D; Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, Canada.
  • Aceto G; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Ho R; Department of Molecular Oncology, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Steinberger J; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Monast A; Department of Biochemistry, McGill University, Montreal, QC, Canada.
  • Pilon V; Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, Canada.
  • Li E; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Ta M; Department of Molecular Oncology, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Ching K; Department of Biochemistry, McGill University, Montreal, QC, Canada.
  • Adams BN; Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, Canada.
  • Negri GL; Department of Biochemistry, McGill University, Montreal, QC, Canada.
  • Choiniere L; Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, Canada.
  • Fu L; Department of Biochemistry, McGill University, Montreal, QC, Canada.
  • Pavlakis K; Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, Canada.
  • Pirrotte P; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Avizonis DZ; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Trent J; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Weissman BE; Department of Biochemistry, McGill University, Montreal, QC, Canada.
  • Klein Geltink RI; Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, Canada.
  • Morin GB; Canada's Michael Smith Genome Science Centre, British Columbia Cancer Research Institute, Vancouver, BC, Canada.
  • Park M; Rosalind & Morris Goodman Cancer Institute, Metabolomics Innovation Resource, McGill University, Montreal, QC, Canada.
  • Huntsman DG; Department of Pathology, McGill University Health Centre, Montreal, QC, Canada.
  • Foulkes WD; Department of Pathology, IASO women's hospital, Athens, Greece.
  • Wang Y; Cancer & Cell Biology Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
  • Huang S; Integrated Mass Spectrometry Shared Resource, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
Nat Commun ; 14(1): 2894, 2023 05 20.
Article in En | MEDLINE | ID: mdl-37210563
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glutamine / Neoplasms Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Canada
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glutamine / Neoplasms Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Canada