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Antisense Oligonucleotide Therapy Decreases IL-1ß Expression and Prolongs Survival in Mutant Nlrp3 Mice.
Kaufmann, Benedikt; de Los Reyes Jiménez, Marta; Booshehri, Laela M; Onyuru, Janset; Leszczynska, Aleksandra; Uri, Anna; Michel, Sven; Klar, Richard; Jaschinski, Frank; Feldstein, Ariel E; Broderick, Lori; Hoffman, Hal M.
Affiliation
  • Kaufmann B; Department of Pediatrics, University of California San Diego, La Jolla, CA.
  • de Los Reyes Jiménez M; Klinik und Poliklinik für Chirurgie, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
  • Booshehri LM; Secarna Pharmaceuticals GmbH & Co. KG, Planegg/Martinsried, Germany.
  • Onyuru J; Department of Pediatrics, University of California San Diego, La Jolla, CA.
  • Leszczynska A; Department of Pediatrics, University of California San Diego, La Jolla, CA.
  • Uri A; Department of Pediatrics, University of California San Diego, La Jolla, CA.
  • Michel S; Secarna Pharmaceuticals GmbH & Co. KG, Planegg/Martinsried, Germany.
  • Klar R; Secarna Pharmaceuticals GmbH & Co. KG, Planegg/Martinsried, Germany.
  • Jaschinski F; Secarna Pharmaceuticals GmbH & Co. KG, Planegg/Martinsried, Germany.
  • Feldstein AE; Secarna Pharmaceuticals GmbH & Co. KG, Planegg/Martinsried, Germany.
  • Broderick L; Department of Pediatrics, University of California San Diego, La Jolla, CA.
  • Hoffman HM; Rady Children's Hospital-San Diego, San Diego, CA.
J Immunol ; 211(2): 287-294, 2023 07 15.
Article in En | MEDLINE | ID: mdl-37256266
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cryopyrin-Associated Periodic Syndromes / NLR Family, Pyrin Domain-Containing 3 Protein Limits: Animals Language: En Journal: J Immunol Year: 2023 Document type: Article Affiliation country: Canada Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cryopyrin-Associated Periodic Syndromes / NLR Family, Pyrin Domain-Containing 3 Protein Limits: Animals Language: En Journal: J Immunol Year: 2023 Document type: Article Affiliation country: Canada Country of publication: United States