Trends and challenges in microfluidic methods for protein manipulation-A review.
Electrophoresis
; 45(1-2): 69-100, 2024 Jan.
Article
in En
| MEDLINE
| ID: mdl-37259641
ABSTRACT
Proteins are important molecules involved in an immensely large number of biological processes. Being capable of manipulating proteins is critical for developing reliable and affordable techniques to analyze and/or detect them. Such techniques would enable the production of therapeutic agents for the treatment of diseases or other biotechnological applications (e.g., bioreactors or biocatalysis). Microfluidic technology represents a potential solution to protein manipulation challenges because of the diverse phenomena that can be exploited to achieve micro- and nanoparticle manipulation. In this review, we discuss recent contributions made in the field of protein manipulation in microfluidic systems using different physicochemical principles and techniques, some of which are miniaturized versions of already established macro-scale techniques.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Microfluidic Analytical Techniques
/
Nanoparticles
Language:
En
Journal:
Electrophoresis
Year:
2024
Document type:
Article
Affiliation country:
Mexico
Publication country:
ALEMANHA
/
ALEMANIA
/
DE
/
DEUSTCHLAND
/
GERMANY