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Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
Haston, Scott; Gonzalez-Gualda, Estela; Morsli, Samir; Ge, Jianfeng; Reen, Virinder; Calderwood, Alexander; Moutsopoulos, Ilias; Panousopoulos, Leonidas; Deletic, Polina; Carreno, Gabriela; Guiho, Romain; Manshaei, Saba; Gonzalez-Meljem, Jose Mario; Lim, Hui Yuan; Simpson, Daniel J; Birch, Jodie; Pallikonda, Husayn A; Chandra, Tamir; Macias, David; Doherty, Gary J; Rassl, Doris M; Rintoul, Robert C; Signore, Massimo; Mohorianu, Irina; Akbar, Arne N; Gil, Jesús; Muñoz-Espín, Daniel; Martinez-Barbera, Juan Pedro.
Affiliation
  • Haston S; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK. Electronic address: scott.haston.13@ucl.ac.uk.
  • Gonzalez-Gualda E; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK.
  • Morsli S; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK.
  • Ge J; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK.
  • Reen V; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK.
  • Calderwood A; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK.
  • Moutsopoulos I; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK.
  • Panousopoulos L; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK.
  • Deletic P; Division of Medicine, University College London, London, UK.
  • Carreno G; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK.
  • Guiho R; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK.
  • Manshaei S; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK.
  • Gonzalez-Meljem JM; Tecnologico de Monterrey, School of Engineering and Sciences, Mexico City, Mexico.
  • Lim HY; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK.
  • Simpson DJ; MRC Human Generics Unit, University of Edinburgh, Edinburgh, UK.
  • Birch J; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK.
  • Pallikonda HA; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK.
  • Chandra T; MRC Human Generics Unit, University of Edinburgh, Edinburgh, UK.
  • Macias D; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK.
  • Doherty GJ; Cambridge University Hospitals NHS Foundation Trust, Department of Oncology, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
  • Rassl DM; Royal Papworth Hospital NHS Foundation Trust. Cambridge Biomedical Campus, Cambridge CB2 0AY, UK.
  • Rintoul RC; Royal Papworth Hospital NHS Foundation Trust. Cambridge Biomedical Campus, Cambridge CB2 0AY, UK; Department of Oncology, University of Cambridge, Cambridge, UK; CRUK Cambridge Centre Thoracic Cancer Programme, Cambridge, UK.
  • Signore M; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK.
  • Mohorianu I; Wellcome-MRC Cambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK.
  • Akbar AN; Division of Medicine, University College London, London, UK.
  • Gil J; MRC London Institute of Medical Sciences (LMS), Du Cane Road, London W12 0NN, UK; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK.
  • Muñoz-Espín D; Early Cancer Institute, Department of Oncology, University of Cambridge, Cambridge, UK; CRUK Cambridge Centre Thoracic Cancer Programme, Cambridge, UK. Electronic address: dm742@cam.ac.uk.
  • Martinez-Barbera JP; Developmental Biology and Cancer Programme, Birth Defects Research Centre, UCL Institute of Child Health, London WC1N 1EH, UK. Electronic address: j.martinez-barbera@ucl.ac.uk.
Cancer Cell ; 41(7): 1242-1260.e6, 2023 07 10.
Article in En | MEDLINE | ID: mdl-37267953
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cellular Senescence / Lung Neoplasms Type of study: Prognostic_studies Limits: Aged / Animals / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2023 Document type: Article
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cellular Senescence / Lung Neoplasms Type of study: Prognostic_studies Limits: Aged / Animals / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2023 Document type: Article