Alterations in the preneoplastic breast microenvironment of <i>BRCA1</i>/<i>2</i> mutation carriers revealed by spatial transcriptomics.

Caputo, Anthony; Vipparthi, Kavya; Bazeley, Peter; Downs-Kelly, Erinn; McIntire, Patrick; Ni, Ying; Hu, Bo; Keri, Ruth A; Karaayvaz, Mihriban

Alterations in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers revealed by spatial transcriptomics.

Caputo, Anthony; Vipparthi, Kavya; Bazeley, Peter; Downs-Kelly, Erinn; McIntire, Patrick; Ni, Ying; Hu, Bo; Keri, Ruth A; Karaayvaz, Mihriban.

Affiliation

Caputo A; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Vipparthi K; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Bazeley P; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Downs-Kelly E; Department of Pathology, Pathology & Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.
McIntire P; Department of Pathology, Pathology & Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.
Ni Y; Center for Immunotherapy & Precision Immuno-Oncology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Hu B; Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Keri RA; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Karaayvaz M; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

bioRxiv ; 2023 May 25.

Article in En | MEDLINE | ID: mdl-37292816

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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Risk_factors_studies Language: En Journal: BioRxiv Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States

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