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Reversing vemurafenib-resistance in primary melanoma cells by combined romidepsin and type I IFN treatment through blocking of tumorigenic signals and induction of immunogenic effects.
Fragale, Alessandra; Stellacci, Emilia; Romagnoli, Giulia; Licursi, Valerio; Parlato, Stefania; Canini, Irene; Remedi, Giacomo; Buoncervello, Maria; Matarrese, Paola; Pedace, Lucia; Ascione, Barbara; Pizzi, Simone; Tartaglia, Marco; D'Atri, Stefania; Presutti, Carlo; Capone, Imerio; Gabriele, Lucia.
Affiliation
  • Fragale A; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità (ISS), Rome, Italy.
  • Stellacci E; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità (ISS), Rome, Italy.
  • Romagnoli G; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità (ISS), Rome, Italy.
  • Licursi V; Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR) of Italy, Rome, Italy.
  • Parlato S; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità (ISS), Rome, Italy.
  • Canini I; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità (ISS), Rome, Italy.
  • Remedi G; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità (ISS), Rome, Italy.
  • Buoncervello M; Research Coordination and Support Service, ISS, Rome, Italy.
  • Matarrese P; Center for Gender-Specific Medicine, ISS, Rome, Italy.
  • Pedace L; Department of Pediatric Haematology/Oncology, Cell and Gene Therapy, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.
  • Ascione B; Center for Gender-Specific Medicine, ISS, Rome, Italy.
  • Pizzi S; Molecular Genetics and Functional Genomics, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.
  • Tartaglia M; Molecular Genetics and Functional Genomics, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.
  • D'Atri S; Molecular Oncology Laboratory, Istituto Dermatopatico dell'Immacolata IDI-IRCCS, Rome, Italy.
  • Presutti C; Department of Biology and Biotechnology "Charles Darwin", Sapienza University, Rome, Italy.
  • Capone I; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità (ISS), Rome, Italy.
  • Gabriele L; Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità (ISS), Rome, Italy.
Int J Cancer ; 153(5): 1080-1095, 2023 Sep 01.
Article in En | MEDLINE | ID: mdl-37293858
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / Melanoma Limits: Humans Language: En Journal: Int J Cancer Year: 2023 Document type: Article Affiliation country: Italy
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon Type I / Melanoma Limits: Humans Language: En Journal: Int J Cancer Year: 2023 Document type: Article Affiliation country: Italy