Early life corticosteroid overexposure: Epigenetic and fetal origins of adult diseases.

Briceño-Pérez, Carlos; Briceño-Sanabria, Liliana; Briceño-Sanabria, Carlos; Reyna-Villasmil, Eduardo

Briceño-Pérez, Carlos; Briceño-Sanabria, Liliana; Briceño-Sanabria, Carlos; Reyna-Villasmil, Eduardo.

Affiliation

Briceño-Pérez C; Department of Obstetrics and Gynecology, University of Zulia, Maracaibo, Venezuela.
Briceño-Sanabria L; Obstetrics and Gynecology, Bayview Surgery Center, Sarasota, Florida, USA.
Briceño-Sanabria C; General Surgery and Plastic Surgery, Amado and Maracaibo Clinics, Maracaibo, Venezuela.
Reyna-Villasmil E; Obstetrics and Gynecology Service, Hospital Central "Dr. Urquinaona", Maracaibo, Venezuela.

Int J Gynaecol Obstet ; 164(1): 40-46, 2024 Jan.

Article in En | MEDLINE | ID: mdl-37318113

Subject(s)

Placenta; Premature Birth; Adult; Pregnancy; Female; Infant, Newborn; Humans; Placenta/metabolism; 11-beta-Hydroxysteroid Dehydrogenase Type 2/genetics; 11-beta-Hydroxysteroid Dehydrogenase Type 2/metabolism; 11-beta-Hydroxysteroid Dehydrogenase Type 2/pharmacology; Hypothalamo-Hypophyseal System/physiology; Pituitary-Adrenal System/physiology; Premature Birth/chemically induced; Fetus; Glucocorticoids/adverse effects; Epigenesis, Genetic; Fetal Development/physiology

Key words

adult diseases; early life programming; epigenetic; fetal corticosteroid overexposure; hypothalamic-pituitary-adrenal axis; prenatal corticosteroid administration; transgenerational effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Placenta / Premature Birth Type of study: Prognostic_studies Limits: Adult / Female / Humans / Newborn / Pregnancy Language: En Journal: Int J Gynaecol Obstet Year: 2024 Document type: Article Affiliation country: Venezuela Country of publication: United States

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