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RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles.
Kratzel, Annika; Thiel, Volker.
Affiliation
  • Kratzel A; Institute of Virology and Immunology (IVI) , Bern, Switzerland.
  • Thiel V; Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
J Cell Biol ; 222(7)2023 07 03.
Article in En | MEDLINE | ID: mdl-37318453
ABSTRACT
SARS-CoV-2 depends on host proteins for successful replication. In this issue, Williams et al. (2023. J. Cell Biol.https//doi.org/10.1083/jcb.202203060) report that the ER membrane-modulating proteins RTN3 and RTN4 are required for the formation of SARS-CoV-2 replication organelles via direct interaction with viral proteins NSP3 and NSP4.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Replication / Carrier Proteins / Nogo Proteins / SARS-CoV-2 / Membrane Proteins / Nerve Tissue Proteins Limits: Humans Language: En Journal: J Cell Biol Year: 2023 Document type: Article Affiliation country: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Replication / Carrier Proteins / Nogo Proteins / SARS-CoV-2 / Membrane Proteins / Nerve Tissue Proteins Limits: Humans Language: En Journal: J Cell Biol Year: 2023 Document type: Article Affiliation country: Switzerland