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Selection, optimization, and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse populations.
Lennon, Niall J; Kottyan, Leah C; Kachulis, Christopher; Abul-Husn, Noura; Arias, Josh; Belbin, Gillian; Below, Jennifer E; Berndt, Sonja; Chung, Wendy; Cimino, James J; Clayton, Ellen Wright; Connolly, John J; Crosslin, David; Dikilitas, Ozan; Velez Edwards, Digna R; Feng, QiPing; Fisher, Marissa; Freimuth, Robert; Ge, Tian; Glessner, Joseph T; Gordon, Adam; Guiducci, Candace; Hakonarson, Hakon; Harden, Maegan; Harr, Margaret; Hirschhorn, Joel; Hoggart, Clive; Hsu, Li; Irvin, Ryan; Jarvik, Gail P; Karlson, Elizabeth W; Khan, Atlas; Khera, Amit; Kiryluk, Krzysztof; Kullo, Iftikhar; Larkin, Katie; Limdi, Nita; Linder, Jodell E; Loos, Ruth; Luo, Yuan; Malolepsza, Edyta; Manolio, Teri; Martin, Lisa J; McCarthy, Li; Meigs, James B; Mersha, Tesfaye B; Mosley, Jonathan; Namjou, Bahram; Pai, Nihal; Pesce, Lorenzo L.
Affiliation
  • Lennon NJ; Broad Institute of MIT and Harvard.
  • Kottyan LC; Cincinnati Children's Hospital Medical Center.
  • Kachulis C; Broad Institute of MIT and Harvard.
  • Arias J; National Institutes of Health.
  • Belbin G; Icahn School Mount Sinai.
  • Below JE; Vanderbilt University Medical Center.
  • Berndt S; National Institutes of Health.
  • Chung W; Columbia University.
  • Cimino JJ; University of Alabama at Birmingham.
  • Clayton EW; Vanderbilt University Medical Center.
  • Connolly JJ; Children's Hospital of Philadelphia.
  • Crosslin D; University of Washington.
  • Dikilitas O; Mayo Clinic.
  • Velez Edwards DR; Vanderbilt University Medical Center.
  • Feng Q; Vanderbilt University Medical Center.
  • Fisher M; Broad Institute of MIT and Harvard.
  • Freimuth R; Mayo Clinic.
  • Ge T; Mass General Brigham.
  • Glessner JT; Children's Hospital of Philadelphia.
  • Gordon A; Northwestern University.
  • Guiducci C; Broad Institute of MIT and Harvard.
  • Hakonarson H; Children's Hospital of Philadelphia.
  • Harden M; Broad Institute of MIT and Harvard.
  • Harr M; Children's Hospital of Philadelphia.
  • Hirschhorn J; Children's Hospital Boston.
  • Hoggart C; Icahn School Mount Sinai.
  • Hsu L; Fred Hutchinson Cancer Center and University of Washington.
  • Irvin R; University of Alabama at Birmingham.
  • Jarvik GP; University of Washington Medical Center.
  • Karlson EW; Mass General Brigham.
  • Khan A; Columbia University.
  • Khera A; Broad Institute of MIT and Harvard.
  • Kiryluk K; Columbia University.
  • Kullo I; Mayo Clinic.
  • Larkin K; Broad Institute of MIT and Harvard.
  • Limdi N; University of Alabama at Birmingham.
  • Linder JE; Vanderbilt University Medical Center.
  • Loos R; University of Copenhagen.
  • Luo Y; Northwestern University.
  • Malolepsza E; Broad Institute of MIT and Harvard.
  • Manolio T; National Institutes of Health.
  • Martin LJ; Cincinnati Children's Hospital Medical Center.
  • McCarthy L; Broad Institute of MIT and Harvard.
  • Meigs JB; Mass General Brigham.
  • Mersha TB; Cincinnati Children's Hospital Medical Center.
  • Mosley J; Vanderbilt University Medical Center.
  • Namjou B; Cincinnati Children's Hospital Medical Center.
  • Pai N; Broad Institute of MIT and Harvard.
  • Pesce LL; Northwestern University.
medRxiv ; 2023 Jun 05.
Article in En | MEDLINE | ID: mdl-37333246
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Language: En Journal: MedRxiv Year: 2023 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Language: En Journal: MedRxiv Year: 2023 Document type: Article