Rapid clearing CT-001 restored hemostasis in mice with coagulopathy induced by activated protein C.

Sim, Derek S; Mallari, Cornell R; Bauzon, Maxine; Hermiston, Terry W

Sim, Derek S; Mallari, Cornell R; Bauzon, Maxine; Hermiston, Terry W.

Affiliation

Sim DS; From the Research Department (D.S.S., C.R.M., T.W.H.), Coagulant Therapeutics Corporation; and Consultant of Coagulant Therapeutics Corporation (M.B.), Berkeley, California.

J Trauma Acute Care Surg ; 96(2): 276-286, 2024 Feb 01.

Article in En | MEDLINE | ID: mdl-37335129

Subject(s)

Blood Coagulation Disorders; Tranexamic Acid; Humans; Mice; Rats; Animals; Protein C/pharmacology; Protein C/therapeutic use; Tranexamic Acid/therapeutic use; Blood Coagulation Disorders/drug therapy; Blood Coagulation Disorders/etiology; Hemostasis; Hemorrhage; Factor VIIa/therapeutic use; Factor VIIa/pharmacology; Polysaccharides/pharmacology; Polysaccharides/therapeutic use; Tomography, X-Ray Computed

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tranexamic Acid / Blood Coagulation Disorders Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Trauma Acute Care Surg Year: 2024 Document type: Article Country of publication: United States

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