Quercetin Alleviates Asthma-Induced Airway Inflammation and Remodeling through Downregulating Periostin via Blocking TGF-ß1/Smad Pathway.

Fang, Yanni; Jin, Wenwen; Guo, Zhen; Hao, Jumei

Fang, Yanni; Jin, Wenwen; Guo, Zhen; Hao, Jumei.

Affiliation

Fang Y; Department of Pediatrics, Yantaishan Hospital, Yantai, China.
Jin W; Department of Clinical Laboratory, Yantai Yuhuangding Hospital, Yantai, China.
Guo Z; Department of Pediatrics, Yantaishan Hospital, Yantai, China.
Hao J; Department of Pediatrics, Yantaishan Hospital, Yantai, China.

Pharmacology ; 108(5): 432-443, 2023.

Article in En | MEDLINE | ID: mdl-37343534

Subject(s)

Anti-Asthmatic Agents; Asthma; Pulmonary Fibrosis; Animals; Mice; Airway Remodeling; Anti-Asthmatic Agents/pharmacology; Asthma/drug therapy; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Fibrosis; Immunosorbents/metabolism; Immunosorbents/pharmacology; Immunosorbents/therapeutic use; Inflammation/metabolism; Lung/pathology; Mice, Inbred BALB C; Ovalbumin/metabolism; Ovalbumin/pharmacology; Pulmonary Fibrosis/drug therapy; Quercetin/pharmacology; Quercetin/therapeutic use; Transforming Growth Factor beta1/metabolism

Key words

Airway inflammation; Airway remodeling; Asthma; Periostin; Quercetin; TGFß1/Smad pathway

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Fibrosis / Asthma / Anti-Asthmatic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Pharmacology Year: 2023 Document type: Article Affiliation country: China Country of publication: Switzerland

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