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Aquaporin 5 in the eye: Expression, function, and roles in ocular diseases.
Zhang, Kaier; Di, Guohu; Bai, Ying; Liu, Anxu; Bian, Wenhan; Chen, Peng.
Affiliation
  • Zhang K; Department of Human Anatomy, Histology and Embryology, School of Basic Medicine, Qingdao University, Qingdao, 266071, Shandong Province, China.
  • Di G; Department of Human Anatomy, Histology and Embryology, School of Basic Medicine, Qingdao University, Qingdao, 266071, Shandong Province, China.
  • Bai Y; Department of Human Anatomy, Histology and Embryology, School of Basic Medicine, Qingdao University, Qingdao, 266071, Shandong Province, China.
  • Liu A; Department of Human Anatomy, Histology and Embryology, School of Basic Medicine, Qingdao University, Qingdao, 266071, Shandong Province, China.
  • Bian W; Department of Human Anatomy, Histology and Embryology, School of Basic Medicine, Qingdao University, Qingdao, 266071, Shandong Province, China.
  • Chen P; Department of Human Anatomy, Histology and Embryology, School of Basic Medicine, Qingdao University, Qingdao, 266071, Shandong Province, China; Clinical Laboratory, Qingdao Central Hospital, The Second Affiliated Hospital of Medical College of Qingdao University, Qingdao, 266042, Shandong Province,
Exp Eye Res ; 233: 109557, 2023 08.
Article in En | MEDLINE | ID: mdl-37380095
ABSTRACT
As a water channel protein, aquaporin 5 (AQP5) is essential for the maintenance of the normal physiological functions of ocular tissues. This review provides an overview of the expression and function of AQP5 in the eye and discusses their role in related eye diseases. Although AQP5 plays a vital role in ocular functions, such as maintaining corneal and lens transparency, regulating water movement, and maintaining homeostasis, some of its functions in ocular tissues are still unclear. Based on the key role of AQP5 in eye function, this review suggests that in the future, eye diseases may be treated by regulating the expression of aquaporin.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Eye Diseases / Lens, Crystalline Limits: Humans Language: En Journal: Exp Eye Res Year: 2023 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Eye Diseases / Lens, Crystalline Limits: Humans Language: En Journal: Exp Eye Res Year: 2023 Document type: Article Affiliation country: China