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Role of efficacy as a determinant of locomotor activation by mu-opioid receptor (MOR) ligands in female and male mice. II. Effects of novel MOR-selective phenylmorphans with high-to-low MOR efficacy.
Santos, Edna J; Nassehi, Nima; Bow, Eric W; Chambers, Dana R; Gutman, Eugene S; Jacobson, Arthur E; Lutz, Joshua A; Marsh, Samuel A; Rice, Kenner C; Sulima, Agnieszka; Selley, Dana E; Negus, S Stevens.
Affiliation
  • Santos EJ; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, USA.
  • Nassehi N; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, USA.
  • Bow EW; Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, NIDA and NIAAA, Bethesda, Maryland, USA.
  • Chambers DR; Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, NIDA and NIAAA, Bethesda, Maryland, USA.
  • Gutman ES; Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, NIDA and NIAAA, Bethesda, Maryland, USA.
  • Jacobson AE; Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, NIDA and NIAAA, Bethesda, Maryland, USA.
  • Lutz JA; Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, NIDA and NIAAA, Bethesda, Maryland, USA.
  • Marsh SA; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, USA.
  • Rice KC; Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, NIDA and NIAAA, Bethesda, Maryland, USA.
  • Sulima A; Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, NIDA and NIAAA, Bethesda, Maryland, USA.
  • Selley DE; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, USA.
  • Negus SS; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, USA.
Pharmacol Res Perspect ; 11(4): e01111, 2023 08.
Article in En | MEDLINE | ID: mdl-37381112

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Buprenorphine / Receptors, Opioid, mu / Analgesics, Opioid Limits: Animals Language: En Journal: Pharmacol Res Perspect Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Buprenorphine / Receptors, Opioid, mu / Analgesics, Opioid Limits: Animals Language: En Journal: Pharmacol Res Perspect Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States