Two-stage generative adversarial networks for metal artifact reduction and visualization in ablation therapy of liver tumors.

PURPOSE: The strong metal artifacts produced by the electrode needle cause poor image quality, thus preventing physicians from observing the surgical situation during the puncture process. To address this issue, we propose a metal artifact reduction and visualization framework for CT-guided ablation therapy of liver tumors. METHODS: Our framework contains a metal artifact reduction model and an ablation therapy visualization model. A two-stage generative adversarial network is proposed to reduce the metal artifacts of intraoperative CT images and avoid image blurring. To visualize the puncture process, the axis and tip of the needle are localized, and then the needle is rebuilt in 3D space intraoperatively. RESULTS: Experiments show that our proposed metal artifact reduction method achieves higher SSIM (0.891) and PSNR (26.920) values than the state-of-the-art methods. The accuracy of ablation needle reconstruction is 2.76 mm average in needle tip localization and 1.64° average in needle axis localization. CONCLUSION: We propose a novel metal artifact reduction and an ablation therapy visualization framework for CT-guided ablation therapy of liver cancer. The experiment results indicate that our approach can reduce metal artifacts and improve image quality. Furthermore, our proposed method demonstrates the potential for displaying the relative position of the tumor and the needle intraoperatively.