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Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties.
Xiao, Pan; Duan, Zongliang; Liu, Zeyu; Chen, Liang; Zhang, Deyan; Liu, Lu; Zhou, Chen; Gan, Jianhua; Dong, Ze; Yang, Cai-Guang.
Affiliation
  • Xiao P; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.
  • Duan Z; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Liu Z; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Chen L; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
  • Zhang D; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Liu L; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Zhou C; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Gan J; University of Chinese Academy of Sciences, Beijing 100049, China.
  • Dong Z; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.
  • Yang CG; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
J Med Chem ; 66(14): 9731-9752, 2023 07 27.
Article in En | MEDLINE | ID: mdl-37418628
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / Leukemia, Myeloid, Acute Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: China Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA / Leukemia, Myeloid, Acute Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: China Country of publication: United States