Sensitive and simple multi-ion detection using organic nanocrystal enrichment in paper analytical devices.
Anal Chim Acta
; 1273: 341451, 2023 Sep 08.
Article
in En
| MEDLINE
| ID: mdl-37423649
ABSTRACT
Microfluidic paper analytical devices (µPADs) are among the most promising platforms for heavy metal ion analysis. On the other hand, achieving simple and highly sensitive analysis of µPADs is challenging. In this study, we developed a simple enrichment method for sensitive multi-ion detection utilizing water-insoluble organic nanocrystals accumulated on µPAD. By combining the enrichment method with multivariate data analysis, three metal ion concentrations in the ion mixtures were simultaneously quantified with high sensitivity owing to the sensitive responses of the organic nanocrystals. In this work, we successfully quantified Zn2+, Cu2+, and Ni2+ at 20 ng L-1 in the mixed ion solution using only two dye indicators with a larger sensitivity improvement than those reported in previous studies. Interference studies revealed possibilities for a practical application in real sample analysis. This developed approach also can be used for other analytes.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Diagnostic_studies
Language:
En
Journal:
Anal Chim Acta
Year:
2023
Document type:
Article
Affiliation country:
Indonesia
Publication country:
HOLANDA
/
HOLLAND
/
NETHERLANDS
/
NL
/
PAISES BAJOS
/
THE NETHERLANDS