The role of TET2-mediated ROBO4 hypomethylation in the development of diabetic retinopathy.

Zhao, Liangliang; Xu, Haitao; Liu, Xin; Cheng, Yan; Xie, Jia'nan

Zhao, Liangliang; Xu, Haitao; Liu, Xin; Cheng, Yan; Xie, Jia'nan.

Affiliation

Zhao L; Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Xu H; Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Liu X; Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Cheng Y; Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, Jilin, China.
Xie J; Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, Jilin, China. jiananxie2014@163.com.

J Transl Med ; 21(1): 455, 2023 07 10.

Article in En | MEDLINE | ID: mdl-37430272

Subject(s)

Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dioxygenases; Hyperglycemia; Animals; Humans; Mice; 5-Methylcytosine; Diabetes Mellitus, Experimental/genetics; Diabetic Retinopathy/genetics; DNA-Binding Proteins/genetics; Endothelial Cells; Neovascularization, Pathologic; Occludin; Receptors, Cell Surface

Key words

Diabetic retinopathy; Hypomethylation; ROBO4; Retinal microangiopathy; TET2

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dioxygenases / Diabetes Mellitus, Experimental / Diabetic Retinopathy / Hyperglycemia Limits: Animals / Humans Language: En Journal: J Transl Med Year: 2023 Document type: Article Affiliation country: China Country of publication: United kingdom

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