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Intralesional amphotericin B in a cat with cutaneous protothecosis.
Roldán Villalobos, Wendie; Ferreira, Tássia; Gmyterco, Vanessa; Bastos, Renata; Bacher, Louise; Jagielski, Tomasz; Ribeiro, Márcio; Farias, Marconi.
Affiliation
  • Roldán Villalobos W; Department of Veterinary Medicine, School of Medicine and Life Sciences, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
  • Ferreira T; Department of Veterinary Medicine, School of Medicine and Life Sciences, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
  • Gmyterco V; Department of Veterinary Medicine, School of Medicine and Life Sciences, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
  • Bastos R; Department of Veterinary Medicine, School of Medicine and Life Sciences, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
  • Bacher L; Department of Veterinary Medicine, School of Medicine and Life Sciences, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
  • Jagielski T; Department of Applied Microbiology, Institute of Microbiology, Faculty of Biology, University of Warsaw, Warsaw, Poland.
  • Ribeiro M; Department of Animal Production and Preventive Veterinary Medicine, School of Veterinary Medicine and Animal Sciences, São Paulo State University-UNESP, Botucatu, SP, Brazil.
  • Farias M; Department of Veterinary Medicine, School of Medicine and Life Sciences, Pontifical Catholic University of Paraná, Curitiba, PR, Brazil.
Vet Dermatol ; 34(6): 629-633, 2023 Dec.
Article in En | MEDLINE | ID: mdl-37443431
ABSTRACT
A domestic cat was presented with nodular lesions on the nose/muzzle and pinnae. Protothecosis was diagnosed through cytological and histopathological examination, and culture. Molecular identification confirmed Prototheca wickerhamii infection. Intralesional application of amphotericin B in conjunction with oral terbinafine resulted in a significant reduction of the nasal lesion and complete resolution of the pinnal lesion, without adverse effects.
Un chat domestique est présenté avec des lésions nodulaires sur le nez/museau et le pavillon auriculaire. La protothécose est diagnostiquée par un examen cytologique et histopathologique, ainsi que par une culture. L'identification moléculaire confirme l'infection par Prototheca wickerhamii. L'application intralésionnelle d'amphotéricine B, associée à la terbinafine orale, permet une réduction significative de la lésion nasale et une résolution complète de la lésion du pavillon auriculaire, sans effets indésirables.
RESUMO
Um gato doméstico foi apresentado com lesões nodulares no nariz/focinho e pavilhões auriculares. Prototecose foi diagnosticada por exame citológico e histopatológico, e cultura. A identificação molecular confirmou a infecção por Prototheca wickerhamii. Aplicação intralesional de anfotericina B associada à terbinafina por via oral resultou em redução significativa da lesão nasal e resolução total da lesão na orelha, sem efeitos adversos.
RESUMEN
Un gato doméstico se presentó con lesiones nodulares en la nariz/hocico y orejas. Se diagnosticó prototecosis mediante examen citológico, histopatológico y cultivo. La identificación molecular confirmó la infección por Prototheca wickerhamii. La aplicación intralesional de anfotericina B junto con terbinafina oral dio como resultado una reducción significativa de la lesión nasal y una resolución completa de la lesión auricular, sin efectos adversos.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prototheca / Skin Diseases, Infectious / Cat Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Vet Dermatol Journal subject: DERMATOLOGIA / MEDICINA VETERINARIA Year: 2023 Document type: Article Affiliation country: Brazil

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prototheca / Skin Diseases, Infectious / Cat Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Vet Dermatol Journal subject: DERMATOLOGIA / MEDICINA VETERINARIA Year: 2023 Document type: Article Affiliation country: Brazil