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Potential Beneficial Effects and Pharmacological Properties of Ergosterol, a Common Bioactive Compound in Edible Mushrooms.
Rangsinth, Panthakarn; Sharika, Rajasekharan; Pattarachotanant, Nattaporn; Duangjan, Chatrawee; Wongwan, Chamaiphron; Sillapachaiyaporn, Chanin; Nilkhet, Sunita; Wongsirojkul, Nichaporn; Prasansuklab, Anchalee; Tencomnao, Tewin; Leung, George Pak-Heng; Chuchawankul, Siriporn.
Affiliation
  • Rangsinth P; Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
  • Sharika R; Department of Pharmacology and Pharmacy, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
  • Pattarachotanant N; Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
  • Duangjan C; Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
  • Wongwan C; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
  • Sillapachaiyaporn C; Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
  • Nilkhet S; Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
  • Wongsirojkul N; Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
  • Prasansuklab A; Department of Transfusion Medicine and Clinical Microbiology, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
  • Tencomnao T; College of Public Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
  • Leung GP; Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
  • Chuchawankul S; Department of Pharmacology and Pharmacy, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Foods ; 12(13)2023 Jun 29.
Article in En | MEDLINE | ID: mdl-37444267
ABSTRACT
Ergosterol is an important sterol commonly found in edible mushrooms, and it has important nutritional value and pharmacological activity. Ergosterol is a provitamin. It has been well established that edible mushrooms are an excellent food source of vitamin D2 because ergosterol is a precursor that is converted to vitamin D2 under ultraviolet radiation. The pharmacological effects of ergosterol, which include antimicrobial, antioxidant, antimicrobial, anticancer, antidiabetic, anti-neurodegenerative, and other activities, have also been reported. This review aims to provide an overview of the available evidence regarding the pharmacological effects of ergosterol and its underlying mechanisms of action. Their potential benefits and applications are also discussed.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Foods Year: 2023 Document type: Article Affiliation country: Thailand
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Foods Year: 2023 Document type: Article Affiliation country: Thailand