A Falciformispora senegalensis grain model in Galleria mellonella larvae.

Ma, Jingyi; Konings, Mickey; Verbon, Annelies; van de Sande, Wendy W J

Ma, Jingyi; Konings, Mickey; Verbon, Annelies; van de Sande, Wendy W J.

Affiliation

Ma J; Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Konings M; Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
Verbon A; Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.
van de Sande WWJ; Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

Med Mycol ; 61(8)2023 Aug 02.

Article in En | MEDLINE | ID: mdl-37451815

Within eumycetoma lesions, the causative agents are embedded in grains. However, the grains differ per causative agent. In this study, we developed a grain model of Falciformispora senegalensis in the larvae of Galleria mellonella. This model can be used in the future to study the efficacy of novel antifungal agents.

Subject(s)

Moths; Mycetoma; Humans; Animals; Antifungal Agents/pharmacology; Larva/microbiology; Amphotericin B/pharmacology; Terbinafine; Itraconazole; Mycetoma/microbiology; Mycetoma/veterinary; Disease Models, Animal; Moths/microbiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mycetoma / Moths Limits: Animals / Humans Language: En Journal: Med Mycol Journal subject: MEDICINA VETERINARIA / MICROBIOLOGIA Year: 2023 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom

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