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Mechanism of the extremely high duplex-forming ability of oligonucleotides modified with N-tert-butylguanidine- or N-tert-butyl-N'- methylguanidine-bridged nucleic acids.
Yamaguchi, Takao; Horie, Naohiro; Aoyama, Hiroshi; Kumagai, Shinji; Obika, Satoshi.
Affiliation
  • Yamaguchi T; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Horie N; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Aoyama H; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
  • Kumagai S; Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Shonan Health Innovation Park, 2-26-1 Muraoka-Higashi, Fujisawa, Kanagawa 251-8555, Japan.
  • Obika S; Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
Nucleic Acids Res ; 51(15): 7749-7761, 2023 08 25.
Article in En | MEDLINE | ID: mdl-37462081
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligonucleotides / Guanidines / Methylguanidine Language: En Journal: Nucleic Acids Res Year: 2023 Document type: Article Affiliation country: Japan Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligonucleotides / Guanidines / Methylguanidine Language: En Journal: Nucleic Acids Res Year: 2023 Document type: Article Affiliation country: Japan Country of publication: United kingdom