New bisabolane-type sesquiterpenoid from Aspergillus sydowii BTBU20213012.
Nat Prod Res
; : 1-8, 2023 Jul 22.
Article
in En
| MEDLINE
| ID: mdl-37480345
ABSTRACT
A new bisabolane-type sesquiterpenoid, named (+)-8-dehydroxylaustrosene (1), along with ten known compounds, penicibisabolanes E (2) and G (3), (+)-austrosene (4), (S)-(+)-11-dehydrosydonic acid (5), sydonic acid (6), (7S,11S)-(+)-12-hydroxysydonic acid (7), (-)-(R)-hydroxysydonic acid (8), pseudaboydin A (9), (-)-(7 R,10R)-iso-10-hydroxysydowic acid (10), lumichrome (11), were identified from the fungus Aspergillus sydowii BTBU20213012 isolated from a marine sediment sample from the Western Pacific. The structures of the compounds were identified by HRESIMS and NMR data analysis. Compound 11 showed weak antimicrobial activity against Staphylococcus aureus with MIC value of 200 µg/mL.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Nat Prod Res
Year:
2023
Document type:
Article