Pulmonary Pathogen-Induced Epigenetic Modifications.
Epigenomes
; 7(3)2023 Jul 06.
Article
in En
| MEDLINE
| ID: mdl-37489401
Epigenetics generally involves genetic control by factors other than our own DNA sequence. Recent research has focused on delineating the mechanisms of two major epigenetic phenomena: DNA methylation and histone modification. As epigenetics involves many cellular processes, it is no surprise that it can also influence disease-associated gene expression. A direct link between respiratory infections, host cell epigenetic regulations, and chronic lung diseases is still unknown. Recent studies have revealed bacterium- or virus-induced epigenetic changes in the host cells. In this review, we focused on respiratory pathogens (viruses, bacteria, and fungi) induced epigenetic modulations (DNA methylation and histone modification) that may contribute to lung disease pathophysiology by promoting host defense or allowing pathogen persistence.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Epigenomes
Year:
2023
Document type:
Article
Affiliation country:
United States
Country of publication:
Switzerland