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Results from a new efficacy and safety analysis of the REGENERATE trial of obeticholic acid for treatment of pre-cirrhotic fibrosis due to non-alcoholic steatohepatitis.
Sanyal, Arun J; Ratziu, Vlad; Loomba, Rohit; Anstee, Quentin M; Kowdley, Kris V; Rinella, Mary E; Sheikh, Muhammad Y; Trotter, James F; Knapple, Whitfield; Lawitz, Eric J; Abdelmalek, Manal F; Newsome, Philip N; Boursier, Jérôme; Mathurin, Philippe; Dufour, Jean-François; Berrey, M Michelle; Shiff, Steven J; Sawhney, Sangeeta; Capozza, Thomas; Leyva, Rina; Harrison, Stephen A; Younossi, Zobair M.
Affiliation
  • Sanyal AJ; Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: arun.sanyal@vcuhealth.org.
  • Ratziu V; Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Institute for Cardiometabolism and Nutrition, Paris, France.
  • Loomba R; University of California, San Diego, La Jolla, CA, USA.
  • Anstee QM; Translational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle Upon Tyne, UK; Newcastle NIHR Biomedical Research Center, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
  • Kowdley KV; Liver Institute Northwest, Seattle, WA, USA.
  • Rinella ME; University of Chicago, Pritzker School of Medicine, Chicago, IL, USA.
  • Sheikh MY; Fresno Clinical Research Center, Fresno, CA, USA.
  • Trotter JF; Baylor Health, Liver Consultants of Texas, Dallas, TX, USA.
  • Knapple W; Arkansas Gastroenterology, North Little Rock, AR, USA.
  • Lawitz EJ; Texas Liver Institute, University of Texas Health San Antonio, San Antonio, TX, USA.
  • Abdelmalek MF; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Newsome PN; National Institute for Health Research Birmingham Biomedical Research Centre, Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University Hospitals Birmingham NHS Foundation Trust and University of Birmingham, Birmingham, UK.
  • Boursier J; Angers University Hospital, Angers University, Angers, France.
  • Mathurin P; Hepatogastroenterology, CHU Lille, Lille, France.
  • Dufour JF; Center for Digestive Diseases, Lausanne, Switzerland.
  • Berrey MM; Intercept Pharmaceuticals, Morristown, NJ, USA.
  • Shiff SJ; Intercept Pharmaceuticals, Morristown, NJ, USA.
  • Sawhney S; Intercept Pharmaceuticals, Morristown, NJ, USA.
  • Capozza T; Intercept Pharmaceuticals, Morristown, NJ, USA.
  • Leyva R; Intercept Pharmaceuticals, Morristown, NJ, USA.
  • Harrison SA; Pinnacle Clinical Research Center, San Antonio, TX, USA.
  • Younossi ZM; Beatty Liver and Obesity Research Program, Center for Liver Diseases, Inova Medicine, Falls Church, VA, USA.
J Hepatol ; 79(5): 1110-1120, 2023 Nov.
Article in En | MEDLINE | ID: mdl-37517454
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2023 Document type: Article Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials Language: En Journal: J Hepatol Journal subject: GASTROENTEROLOGIA Year: 2023 Document type: Article Country of publication: Netherlands