Accumulation of TERT in mitochondria exerts two opposing effects on apoptosis.

Ebata, Hiroshi; Shima, Tomohiro; Iizuka, Ryo; Uemura, Sotaro

Ebata, Hiroshi; Shima, Tomohiro; Iizuka, Ryo; Uemura, Sotaro.

Affiliation

Ebata H; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Japan.
Shima T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Japan.
Iizuka R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Japan.
Uemura S; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Japan.

FEBS Open Bio ; 13(9): 1667-1682, 2023 09.

Article in En | MEDLINE | ID: mdl-37525387

Subject(s)

Mitochondria; Telomerase; Humans; HeLa Cells; Mitochondria/metabolism; Telomerase/genetics; Telomerase/metabolism; Telomerase/pharmacology; Cell Nucleus/metabolism; DNA-Directed RNA Polymerases; Apoptosis

Key words

TERT; apoptosis; live-cell imaging; mitochondria; oxidative stress

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Telomerase / Mitochondria Type of study: Prognostic_studies Limits: Humans Language: En Journal: FEBS Open Bio Year: 2023 Document type: Article Affiliation country: Japan

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