Blood-Brain Barrier (BBB)-Crossing Strategies for Improved Treatment of CNS Disorders.

Zhang, Wandong

Zhang, Wandong.

Affiliation

Zhang W; Human Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, ON, Canada. Wandong.Zhang@nrc-cnrc.gc.ca.

Handb Exp Pharmacol ; 284: 213-230, 2024.

Article in En | MEDLINE | ID: mdl-37528323

Subject(s)

Blood-Brain Barrier; Brain; Humans; Blood-Brain Barrier/metabolism; Brain/metabolism; Biological Transport/physiology; Central Nervous System; Drug Delivery Systems; Pharmaceutical Preparations/metabolism

Key words

ABC transporters; AI-assisted drug development; Adsorptive-mediated transcytosis; Blood-brain barrier (BBB); Brain drug delivery; Carrier-mediated transcytosis (CMT); Cell-/BBB-penetrating peptides; Cell-mediated drug delivery; Focused ultrasound; Intranasal drug delivery; Nanoparticles; Neurovascular unit; Receptor-mediated transcytosis (RMT); Viral vector and gene delivery

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Blood-Brain Barrier Limits: Humans Language: En Journal: Handb Exp Pharmacol Year: 2024 Document type: Article Affiliation country: Canada Country of publication: Germany

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