Chronic-binge ethanol feeding aggravates systemic dyslipidemia in <i>Ldlr</i><sup>-/-</sup> mice, thereby accelerating hepatic fibrosis.

Hoebinger, Constanze; Rajcic, Dragana; Silva, Beatriz; Hendrikx, Tim

Chronic-binge ethanol feeding aggravates systemic dyslipidemia in Ldlr^-/- mice, thereby accelerating hepatic fibrosis.

Hoebinger, Constanze; Rajcic, Dragana; Silva, Beatriz; Hendrikx, Tim.

Affiliation

Hoebinger C; Department of Laboratory Medicine, Medical University Vienna, Vienna, Austria.
Rajcic D; Department of Laboratory Medicine, Medical University Vienna, Vienna, Austria.
Silva B; Department of Laboratory Medicine, Medical University Vienna, Vienna, Austria.
Hendrikx T; Department of Biochemistry, Chemistry Institute, University of Sao Paulo, Sao Paulo, Brazil.

Front Endocrinol (Lausanne) ; 14: 1148827, 2023.

Article in En | MEDLINE | ID: mdl-37560305

Subject(s)

Dyslipidemias; Fatty Liver; Hypercholesterolemia; Hyperlipidemias; Liver Diseases, Alcoholic; Female; Mice; Humans; Animals; Ethanol/toxicity; Mice, Inbred C57BL; Fatty Liver/chemically induced; Fatty Liver/genetics; Liver Diseases, Alcoholic/complications; Liver Diseases, Alcoholic/metabolism; Liver Cirrhosis/chemically induced; Liver Cirrhosis/genetics; Hypercholesterolemia/complications; Hyperlipidemias/complications; Dyslipidemias/complications; Cholesterol; Triglycerides; Lipids

Key words

Ldlr-/- mice; alcohol-associated liver disease (ALD); alcoholic fibrosis; dyslipidemia; hypercholesterolemia; inflammation; low-density lipoprotein receptor (LDLR)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dyslipidemias / Fatty Liver / Hypercholesterolemia / Hyperlipidemias / Liver Diseases, Alcoholic Limits: Animals / Female / Humans Language: En Journal: Front Endocrinol (Lausanne) Year: 2023 Document type: Article Affiliation country: Austria Country of publication: Switzerland

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