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Towards a youth mental health paradigm: a perspective and roadmap.
Uhlhaas, Peter J; Davey, Christopher G; Mehta, Urvakhsh Meherwan; Shah, Jai; Torous, John; Allen, Nicholas B; Avenevoli, Shelli; Bella-Awusah, Tolulope; Chanen, Andrew; Chen, Eric Y H; Correll, Christoph U; Do, Kim Q; Fisher, Helen L; Frangou, Sophia; Hickie, Ian B; Keshavan, Matcheri S; Konrad, Kerstin; Lee, Francis S; Liu, Cindy H; Luna, Beatriz; McGorry, Patrick D; Meyer-Lindenberg, Andreas; Nordentoft, Merete; Öngür, Dost; Patton, George C; Paus, Tomás; Reininghaus, Ulrich; Sawa, Akira; Schoenbaum, Michael; Schumann, Gunter; Srihari, Vinod H; Susser, Ezra; Verma, Swapna K; Woo, T Wilson; Yang, Lawrence H; Yung, Alison R; Wood, Stephen J.
Affiliation
  • Uhlhaas PJ; Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK. peter.uhlhaas@charite.de.
  • Davey CG; Department of Child and Adolescent Psychiatry, Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. peter.uhlhaas@charite.de.
  • Mehta UM; Department of Psychiatry, The University of Melbourne, Carlton, VIC, Australia.
  • Shah J; Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
  • Torous J; Department of Psychiatry, McGill University, Montreal, QC, Canada.
  • Allen NB; Division of Digital Psychiatry and Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Avenevoli S; Department of Psychology, University of Oregon, Eugene, OR, USA.
  • Bella-Awusah T; Office of the Director, National Institute of Mental Health, Bethesda, MD, USA.
  • Chanen A; Department of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
  • Chen EYH; Orygen: National Centre of Excellence in Youth Mental Health, Parkville, VIC, Australia.
  • Correll CU; Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia.
  • Do KQ; Department of Psychiatry, University of Hong Kong, Hong Kong, China.
  • Fisher HL; Department of Child and Adolescent Psychiatry, Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Frangou S; Departments of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hostra/Northwell, Hempstead, NY, USA.
  • Hickie IB; Department of Psychiatry, The Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, USA.
  • Keshavan MS; Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland.
  • Konrad K; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Lee FS; ESRC Centre for Society and Mental Health, King's College London, London, UK.
  • Liu CH; Department of Psychiatry, The University of British Columbia, Vancouver, BC, Canada.
  • Luna B; Brain and Mind Centre, University of Sydney, Camperdown, NSW, Australia.
  • McGorry PD; Department of Psychiatry, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
  • Meyer-Lindenberg A; Child Neuropsychology Section, Department of Child and Adolescent Psychiatry, RWTH, Aachen, Germany.
  • Nordentoft M; JARA-Brain Institute II, Molecular Neuroscience and Neuroimaging, Research Center Jülich, Jülich, Germany.
  • Öngür D; Department of Psychiatry, Weill Cornell Cornell Medicall College, New York, NY, USA.
  • Patton GC; Departments of Pediatrics and Psychiatry, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, USA.
  • Paus T; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
  • Reininghaus U; Orygen: National Centre of Excellence in Youth Mental Health, Parkville, VIC, Australia.
  • Sawa A; Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia.
  • Schoenbaum M; Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.
  • Schumann G; CORE-Copenhagen Research Centre for Mental Health, Mental Health Center Copenhagen, University of Copenhagen, Faculty of Health and Medical Sciences, Department of Clinical Medicine, Hellerup, Denmark.
  • Srihari VH; McLean Hospital/Harvard Medical School, Belmont, MA, USA.
  • Susser E; Centre for Adolescent Health, Murdoch Children's Research Institute, University of Melbourne, Parkville, VIC, Australia.
  • Verma SK; Departments of Psychiatry and Neuroscience, Faculty of Medicine and Centre Hospitalier Universitaire Sainte Justine, University of Montreal, Montreal, QC, Canada.
  • Woo TW; Department of Psychology and Psychiatry, University of Toronto, Toronto, ON, Canada.
  • Yang LH; Department of Public Mental Health, Central Institute of Mental Health, Medical Faculty Mannheim, Mannheim, Germany.
  • Yung AR; Centre for Epidemiology and Public Health, Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Wood SJ; The John Hopkins Schizophrenia Center, Johns Hopkins University, Baltimore, MD, USA.
Mol Psychiatry ; 28(8): 3171-3181, 2023 Aug.
Article in En | MEDLINE | ID: mdl-37580524
ABSTRACT
Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health. This perspective addresses interactions between risk and protective factors and brain development as key pillars accounting for the emergence of psychopathology in youth. Moreover, we propose that novel approaches towards early diagnosis and interventions are required that reflect the evolution of emerging psychopathology, the importance of novel service models, and knowledge exchange between science and practitioners. Taken together, we propose a transformative early intervention paradigm for research and clinical care that could significantly enhance mental health in young people and initiate a shift towards the prevention of severe mental disorders.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mental Health / Mental Disorders Type of study: Prognostic_studies / Screening_studies Limits: Adolescent / Humans Language: En Journal: Mol Psychiatry Journal subject: BIOLOGIA MOLECULAR / PSIQUIATRIA Year: 2023 Document type: Article Affiliation country: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mental Health / Mental Disorders Type of study: Prognostic_studies / Screening_studies Limits: Adolescent / Humans Language: En Journal: Mol Psychiatry Journal subject: BIOLOGIA MOLECULAR / PSIQUIATRIA Year: 2023 Document type: Article Affiliation country: United kingdom
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